Comments on Pain-Topics.org News/Research UPDATES: New Opioid, Exalgo, on Slippery Slope of REMS

I have been taking this medicine for 1 month and h...

2010-10-09T14:32:10.853-05:00

I have been taking this medicine for 1 month and haven't seen a huge relief in pain. I was taking oxycontin 30mg and was not getting any relief at all. This Med is new and is supposed to be the safest and strongest out there. I am not very impressed with it at all. I wish there was something out there that would help me......

MY HUSBAND TAKES THIS MEDICATION AND HE FOR TWO WE...

2010-08-21T17:47:44.691-05:00

MY HUSBAND TAKES THIS MEDICATION AND HE FOR TWO WEEKS NOW AND HE HAS BEEN THRU A LOT OF WITHDRAWLS FROM OXY THAT HE WAS ON NOW THIS MEDICATION SORRY COMES OUT IN STOOL THERE IS NO WAY THAT THE MEDICATION COMES OUT THE TINY PIN HOLE JUST A INDENT OF A HOLE THAT IS IN A DIFFERENT PLACE ON ALL THE PILLS IT SAID IT TAKES TWO THREE DAYS TO WORK WELL HE ALREADY PASSED IN STOOL IT WAY BEFORE IT EVER

I have recently been prescribed Exalgo for long-te...

2010-07-16T17:59:11.041-05:00

I have recently been prescribed Exalgo for long-term chronic pain. To answer the question about "crushablilty" : I accidently dropped one on the floor and then rolled over it with my very heavy desk chair (heavy enough to pulverize any other pill I've ever come across). Aside from some bruising to "paint" (the thin orange coating on which the pill's information is

In reference to above comment… we didn’t understan...

2010-02-23T21:05:28.835-06:00

In reference to above comment… we didn’t understand the FDA panel's concerns either, since there was nothing in the background data to suggest any exceptional abuse potential for Exalgo, via crushing or otherwise. Jurnista isn’t marketed in the U.S. and, while it appears to use the same technology as Exalgo, perhaps it is somehow different (ie, crushproof?).

The FDA is expected to

I don't understand this comment here: -> A...

2010-02-23T19:56:05.195-06:00

I don't understand this comment here:

-> According to panel chairman, Jeffrey Kirsch, MD, the panel felt Exalgo was "…very prone to crushing and other methods of abuse. On the spectrum of abuse, I think it's toward the top."

According to drug users online, Jurnista (exactly the same as exalgo) is unbreakable! This is coming from guys who are trying to

Onsolis and possibly Exalgo getting approval with ...

2009-09-28T13:29:14.268-05:00

Onsolis and possibly Exalgo getting approval with their own proprietary opioid REMS is the beginning of a mudslide which could result in the FDA losing interest in developing a unified, comprehensive opioid REMS because the drug manufacturers bring them to the approval table already figured out, making things very easy for the FDA to leave them untouched (or slightly modified). This then ignores